| Team | Points | Passing yards | Rushing yards | Carries | Turnovers |
|---|---|---|---|---|---|
| San Francisco 49ers | 10 | 94 | 153 | 27 | 2 |
| Buffalo Bills | 35 | 152 | 220 | 38 | 0 |
| Passing | C/ATT | YDS | TD | INT | SACKS |
|---|---|---|---|---|---|
| Brock Purdy | 11/18 | 94 | 0 | 0 | 2 |
| Rushing | CAR | YDS | TD | LONG |
|---|---|---|---|---|
| Jordan Mason | 13 | 78 | 0 | 28 |
| Christian McCaffrey | 7 | 53 | 0 | 19 |
| Isaac Guerendo | 4 | 19 | 1 | 15 |
| Brock Purdy | 2 | 4 | 0 | 3 |
| Kyle Juszczyk | 1 | -1 | 0 | -1 |
| Receiving | REC | TGT | YDS | TD | LONG |
|---|---|---|---|---|---|
| Jauan Jennings | 3 | 5 | 56 | 0 | 26 |
| Deebo Samuel Sr. | 4 | 5 | 20 | 0 | 7 |
| Christian McCaffrey | 2 | 3 | 14 | 0 | 12 |
| George Kittle | 1 | 2 | 7 | 0 | 7 |
| Ricky Pearsall | 0 | 1 | 0 | 0 | — |
| Isaac Guerendo | 1 | 1 | -3 | 0 | -3 |
| Kicking | FG | LONG | XP |
|---|---|---|---|
| Jake Moody | 1/3 | 33 | 1/1 |
| Defence | TKL | SOLO | SACKS | INT | PD |
|---|---|---|---|---|---|
| Ji'Ayir Brown | 8 | 3 | 0 | 0 | 0 |
| Renardo Green | 6 | 5 | 0 | 0 | 1 |
| De'Vondre Campbell | 5 | 2 | 0 | 0 | 0 |
| Charvarius Ward | 5 | 1 | 0 | 0 | 0 |
| Malik Mustapha | 5 | 1 | 0 | 0 | 1 |
| Fred Warner | 4 | 2 | 0 | 0 | 0 |
| Yetur Gross-Matos | 4 | 1 | 0 | 0 | 0 |
| Nick McCloud | 4 | 1 | 0 | 0 | 0 |
| Passing | C/ATT | YDS | TD | INT | SACKS |
|---|---|---|---|---|---|
| Josh Allen | 13/17 | 148 | 2 | 0 | 0 |
| Mitchell Trubisky | 1/1 | 4 | 0 | 0 | 0 |
| Rushing | CAR | YDS | TD | LONG |
|---|---|---|---|---|
| James Cook | 14 | 107 | 1 | 65 |
| Ray Davis | 11 | 63 | 1 | 13 |
| Ty Johnson | 5 | 28 | 0 | 8 |
| Josh Allen | 3 | 18 | 1 | 8 |
| Curtis Samuel | 1 | 7 | 0 | 7 |
| Mitchell Trubisky | 4 | -3 | 0 | 0 |
| Receiving | REC | TGT | YDS | TD | LONG |
|---|---|---|---|---|---|
| Dawson Knox | 2 | 2 | 56 | 0 | 39 |
| Khalil Shakir | 4 | 7 | 30 | 0 | 18 |
| Quintin Morris | 1 | 1 | 14 | 0 | 14 |
| James Cook | 1 | 1 | 13 | 0 | 13 |
| Amari Cooper | 3 | 3 | 12 | 0 | 7 |
| Ty Johnson | 1 | 1 | 9 | 0 | 9 |
| Mack Hollins | 1 | 1 | 7 | 1 | 7 |
| Ray Davis | 1 | 1 | 4 | 0 | 4 |
| Zach Davidson | 0 | 1 | 0 | 0 | — |
| Kicking | FG | LONG | XP |
|---|---|---|---|
| Tyler Bass | 0/1 | — | 5/5 |
| Defence | TKL | SOLO | SACKS | INT | PD |
|---|---|---|---|---|---|
| Terrel Bernard | 9 | 3 | 0 | 0 | 0 |
| Taron Johnson | 6 | 3 | 0 | 0 | 0 |
| Taylor Rapp | 6 | 3 | 0 | 0 | 0 |
| Rasul Douglas | 5 | 3 | 0 | 0 | 0 |
| Matt Milano | 5 | 2 | 0 | 0 | 0 |
| Damar Hamlin | 5 | 4 | 0 | 0 | 0 |
| Greg Rousseau | 4 | 4 | 1 | 0 | 0 |
| DaQuan Jones | 3 | 1 | 0 | 0 | 0 |
Passing yards are before sacks. Defence shows each side's top tacklers.