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Game

San Francisco 49ers vs Indianapolis Colts: result and box score, 22 December 2025

NFL games
Final, Lucas Oil Stadium
11–4
@
8–7
48FINAL27
Box score →

Matchup

Last 15 games
24.5Points per game27.9
22.7Points allowed21.7
261.3Passing yards242.6
103.8Rushing yards132.1
-0.6Turnover margin0.27

Injuries

Kurtis RourkeSF, KneeOut
Renardo GreenSF, NeckOut
Ricky PearsallSF, KneeOut
Yetur Gross-MatosSF, HamstringQuestionable
Christian McCaffreySF, Not injury related - resting playerFull Participation in Practice
Dee WintersSF, WristFull Participation in Practice
Jordan ElliottSF, KneeFull Participation in Practice
Nick MartinSF, ConcussionDid Not Participate In Practice
Sam OkuayinonuSF, AnkleFull Participation in Practice
Spencer BurfordSF, KneeFull Participation in Practice
Tatum BethuneSF, AnkleFull Participation in Practice
Trent WilliamsSF, Not injury related - resting playerFull Participation in Practice
Anthony GouldIND, FootOut
NFL matchups49ers @ Colts
Away, 11–4
Home, 8–7
Tue 23 Dec, 01:15 UK, Lucas Oil Stadium
48 – 27

Box score

Box score

TeamPointsPassing yardsRushing yardsCarriesTurnovers
San Francisco 49ers48295 145311
Indianapolis Colts27277 58201

San Francisco 49ers

PassingC/ATTYDSTDINTSACKS
Brock Purdy25/34295511
RushingCARYDSTDLONG
Christian McCaffrey21117024
Brian Robinson520011
Brock Purdy21109
Mac Jones3-30—
ReceivingRECTGTYDSTDLONG
George Kittle78115126
Jauan Jennings5671121
Christian McCaffrey6829210
Kendrick Bourne3527014
Demarcus Robinson2223122
Skyy Moore1123023
Jake Tonges12707
Brian Robinson0100—
KickingFGLONGXP
Eddy Pineiro2/3386/6
DefenceTKLSOLOSACKSINTPD
Ji'Ayir Brown95000
Tatum Bethune94001
Malik Mustapha83000
Darrell Luter Jr.65001
Upton Stout63002
Deommodore Lenoir32000
Sam Okuayinonu31000
Kalia Davis30001

Indianapolis Colts

PassingC/ATTYDSTDINTSACKS
Philip Rivers23/35277212
Riley Leonard0/10000
RushingCARYDSTDLONG
Jonathan Taylor164617
Tyler Goodson3906
Josh Downs1303
ReceivingRECTGTYDSTDLONG
Alec Pierce4486233
Josh Downs5965018
Jonathan Taylor3333019
Michael Pittman4532014
Tyler Warren3930019
Mo Alie-Cox221608
Andrew Ogletree1211011
Ameer Abdullah11404
Coleman Owen0100—
KickingFGLONGXP
Blake Grupe2/2513/3
DefenceTKLSOLOSACKSINTPD
Camryn Bynum75011
Germaine Pratt64001
Nick Cross63000
DeForest Buckner54000
Samson Ebukam43000
Zaire Franklin42001
Cameron Mitchell43000
Kenny Moore II32000

Passing yards are before sacks. Defence shows each side's top tacklers.

Team comparison

Last 15 games before this one
49ersColts
24.5 Points per game 27.9
22.7 Points allowed 21.7
261.3 Passing yards 242.6
103.8 Rushing yards 132.1
-0.6 Turnover margin 0.27

Injuries

Out Kurtis RourkeSF, Knee
Out Renardo GreenSF, Neck
Out Ricky PearsallSF, Knee
Questionable Yetur Gross-MatosSF, Hamstring
Full Participation in Practice Christian McCaffreySF, Not injury related - resting player
Full Participation in Practice Dee WintersSF, Wrist
Full Participation in Practice Jordan ElliottSF, Knee
Did Not Participate In Practice Nick MartinSF, Concussion
Full Participation in Practice Sam OkuayinonuSF, Ankle
Full Participation in Practice Spencer BurfordSF, Knee
Full Participation in Practice Tatum BethuneSF, Ankle
Full Participation in Practice Trent WilliamsSF, Not injury related - resting player
Out Anthony GouldIND, Foot
Out Anthony RichardsonIND, Eye